Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013728 | 0.98 | ATM (0.36) | ATMALDH1A1TSHRHPGDHCAR2 | |
| SCHEMBL3244622 | 0.89 | — | — | |
| SCHEMBL27648827 | 0.79 | — | — | |
| SCHEMBL29128906 | 0.76 | ALDH1A1 (0.36) | ATMALDH1A1TSHRHCAR2PLA2G4B | |
| SCHEMBL3244513 | 0.74 | TSHR (0.34) | TSHR | |
| SCHEMBL28207421 | 0.73 | TSHR (0.48) | ATMALDH1A1TSHRHPGDHCAR2 | |
| SCHEMBL28014411 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL2850575 | 0.72 | TSHR (0.39) | ATMALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL3244610 | 0.72 | — | — | |
| SCHEMBL1879488 | 0.72 | NAAA (0.48) | ATMALDH1A1TSHRHPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627621-B | Tetrahydropyran-4-one and process for preparing pyran-4-one | UBE INDUSTRIES | 2015-05-27 | — | — | CN | disclosed |
| US-7745649-B2 | Processes for preparing tetrahydropyran-4-one and pyran-4-one | UBE INDUSTRIES, LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20070078272-A1 | Processes for preparing tetrahydropyran-4-one and pyran-4-one | UBE INDUSTRIES, LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1700853-A1 | PROCESSES FOR PRODUCING TETRAHYDROPYRAN-4-ONE AND PYRAN-4-ONE | Ube Industries, Ltd. (JP) | 2006-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078272-A1 | Processes for preparing tetrahydropyran-4-one and pyran-4-one | ADH1A, ADH1C, ADH5 | ATM 3449/4885ALDH1A1 29/4885TSHR 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.