Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476989 | 0.88 | ABCB11 (0.46) | ABCB11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL25338189 | 0.82 | PDGFRA (0.43) | KDM4ELMNAHPGDALDH1A1HTT | |
| SCHEMBL28977333 | 0.82 | CYP4F2 (0.37) | MEN1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL9300394 | 0.82 | MEN1 (0.39) | ABCB11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1051164 | 0.78 | CREBBP (0.50) | MEN1KMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL29386752 | 0.78 | CREBBP (0.50) | MEN1KMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL3554094 | 0.78 | KMT2A (0.42) | ABCB11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3562648 | 0.78 | KDM4E (0.49) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL8606262 | 0.76 | AKR1C3 (0.55) | KMT2AMAPTHPGDPOLB | |
| SCHEMBL8364452 | 0.76 | CFD (0.35) | MEN1KMT2AKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894330-A | Synthesis method and application of 1-acetyl-1H-indol-3-yl acetate derivative | 吉林医药学院 | 2023-04-04 | — | — | CN | disclosed |
| WO-2010015589-A1 | BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS AS PDE5 INHIBITORS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |