SCHEMBL3242289

SCHEMBL3242289

CC(=O)C12CC3CC(CC1C3)C2

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.39
EPHX1 P07099 3/20 0.38
P2RX7 Q99572 1/20 0.38
CNR2 P34972 1/20 0.38
EPHX2 P34913 3/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
NPC1 O15118 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837434 1.00 HSD11B1 (0.39) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL927164 0.78 P2RX7 (0.42) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL392678 0.78 THRB (0.40) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL23453794 0.78 THRB (0.40) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL838918 0.78 THRB (0.40) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL1326077 0.76 ALDH1A1 (0.42) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL20194631 0.76 CNR2 (0.41) HSD11B1EPHX1P2RX7CNR2EPHX2
SCHEMBL5969631 0.76 EPHX1 (0.35) HSD11B1EPHX1EPHX2ALDH1A1GAA
SCHEMBL8709524 0.76 GLA (0.43) HSD11B1EPHX1P2RX7EPHX2ALDH1A1
SCHEMBL18434166 0.73 HSD11B1 (0.43) HSD11B1EPHX1P2RX7CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908473-B1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHINETSU CHEMICAL CO (JP) 2006-02-01 EP claimed
EP-2968082-B1 PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS UNILEVER PLC (GB) 2017-02-01 EP disclosed
WO-2010011824-A1 NOVEL XANTHINE COMPOUNDS CONCERT PHARMACEUTICALS, INC. (US) 2010-01-28 WO disclosed
EP-0908473-B1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHINETSU CHEMICAL CO (JP) 2006-02-01 EP disclosed
US-6613844-B2 Polyhydroxystyrene type polymer containing acid labile groups, endcapped and optionally crosslinked; improved alkali dissolution contrast, sensitivity, resolution, plasma etching resistance, heat resistance, and reproducibility SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-09-02 US disclosed
US-20030013832-A1 Novel styrene polymer, chemically amplified positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-01-16 US disclosed
US-6384169-B1 POLYHYDROXYSTYRENE WITH ACID LABILE GROUP, MODIFIED AT ENDS WITH ALKYLS, ESTERS OR ALCOHOLS; INCREASED DISSOLUTION RATE, HIGH SENSITIVITY AND RESOLUTION; RESIST PATTERNS HAVE PLASMA ETCHING RESISTANCE, HEAT RESISTANCE, REPRODUCIBILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-07 US disclosed
EP-0908473-A1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-04-14 EP disclosed