SCHEMBL3242298

SCHEMBL3242298

CC[C@@H](CO)n1cc(OC(=O)O)c(=O)c2cc(Cc3cccc(Cl)c3F)cc(OC(C)C)c21

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 1/20 0.44
P2RX7 Q99572 1/20 0.31
LMNA P02545 1/20 0.31
PDE10A Q9Y233 1/20 0.30
CFD P00746 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243702 0.94 METTL3 (0.43) METTL3
SCHEMBL3240029 0.92 METTL3 (0.49) METTL3LMNAPDE10ACFD
SCHEMBL3241758 0.91 METTL3 (0.43) METTL3
SCHEMBL1044583 0.91 METTL3 (0.54) METTL3P2RX7LMNAPDE10ACFD
SCHEMBL1044585 0.91 METTL3 (0.54) METTL3P2RX7LMNAPDE10ACFD
SCHEMBL3239885 0.91 METTL3 (0.48) METTL3P2RX7LMNACFDHIF1A
SCHEMBL3237655 0.90 METTL3 (0.54) METTL3P2RX7CFDHIF1A
SCHEMBL3241874 0.88 METTL3 (0.45) METTL3CFDHIF1A
SCHEMBL3241563 0.86 METTL3 (0.48) METTL3LMNACFD
SCHEMBL3242029 0.86 METTL3 (0.43) METTL3P2RX7CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1564210-B9 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS JAPAN TOBACCO INC (JP) 2010-03-31 EP claimed
EP-1564210-B1 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS JAPAN TOBACCO INC (JP) 2009-09-16 EP claimed