Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538118 | 0.94 | TAAR1 (0.45) | TAAR1MAOBLMNACYP19A1 | |
| SCHEMBL26908283 | 0.92 | TAAR1 (0.43) | TAAR1MAOBLMNACHRM2 | |
| SCHEMBL15453289 | 0.92 | TAAR1 (0.43) | TAAR1MAOBLMNACHRM2 | |
| SCHEMBL5539547 | 0.92 | TAAR1 (0.43) | TAAR1MAOBLMNACHRM2 | |
| SCHEMBL65960 | 0.86 | TAAR1 (0.50) | TAAR1MAOBAOC3IDO1LOXL2 | |
| SCHEMBL28969259 | 0.83 | TAAR1 (0.43) | TAAR1MAOBLMNACYP19A1AOC3 | |
| SCHEMBL1842465 | 0.81 | MAOB (0.53) | TAAR1MAOBAOC3IDO1LOXL2 | |
| SCHEMBL3246238 | 0.78 | CYP2A6 (0.46) | TAAR1CHRM2IDO1 | |
| SCHEMBL3245743 | 0.78 | TAAR1 (0.46) | TAAR1MAOBLMNA | |
| SCHEMBL13557815 | 0.78 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867674-A | A kind of new salt of substituted heterocycle fused gamma-carbolines and preparation method thereof and crystal form | 上海度德医药科技有限公司 | 2019-06-11 | — | — | CN | claimed |
| EP-0348460-A1 | POLYCYCLICAMINES WITH PSYCHOTROPIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-03 | — | — | EP | claimed |
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |
| EP-3820886-A1 | RADIOLABELED MELANOCORTIN 1 RECEPTOR-SPECIFIC ALPHA-MELANOCYTE-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY | Provincial Health Services Authority (CA) | 2021-05-19 | — | — | EP | disclosed |
| CN-110430879-A | Novel compositions and methods | INTRA CELLULAR THERAPIES INC | 2019-11-08 | — | — | CN | disclosed |
| US-9414588-B2 | Herbicide composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-16 | — | — | US | disclosed |
| US-9414588-B2 | Herbicide composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-16 | — | — | US | disclosed |
| EP-2713755-B1 | CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-02-24 | — | — | EP | disclosed |
| US-20150289505-A1 | HERBICIDE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20150289505-A1 | HERBICIDE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-15 | — | — | US | disclosed |
| US-9101140-B2 | Cyclohexanone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-11 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20040034015-A1 | Substituted heterocycle fused gamma-carbolines | ROBICHAUD ALBERT J (US) | 2004-02-19 | — | — | US | disclosed |
| WO-2003080553-A1 | CYCLOPENTENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-10-02 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-0987248-B1 | Amide derivatives and their therapeutic use | WELLCOME FOUND (GB) | 2002-09-04 | — | — | EP | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0987248-A1 | Amide derivatives and their therapeutic use | THE WELLCOME FOUNDATION LIMITED (GB) | 2000-03-22 | — | — | EP | disclosed |
| US-4464363-A | HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS | MERCK & CO., INC. (US) | 1984-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150289505-A1 | HERBICIDE COMPOSITION | DDT, DHFR, DERL1 | TAAR1 550/4885MAOB 150/4885LMNA 4541/4885 |
| US-20040034015-A1 | Substituted heterocycle fused gamma-carbolines | HCRTR1, HTR2C, OPRK1 | TAAR1 83/4885MAOB 105/4885LMNA 1683/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | TAAR1 436/4885MAOB 860/4885LMNA 1519/4885 |
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | TAAR1 3429/4885MAOB 429/4885LMNA 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.