Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780510 | 0.83 | ALDH1A1 (0.38) | RAB9ASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL5662615 | 0.77 | LOXL2 (0.35) | SMN1; SMN2KDM4EMAPT | |
| SCHEMBL643420 | 0.77 | MAPT (0.38) | RAB9ANPC1ALDH1A1MAPTGFER | |
| SCHEMBL7763429 | 0.77 | MEN1 (0.41) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13685302 | 0.77 | LPL (0.41) | KDM4E | |
| SCHEMBL11503093 | 0.77 | RXRA (0.41) | ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL5603701 | 0.77 | ALDH1A1 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6376616 | 0.75 | PPARA (0.44) | KMT2AMEN1PPARA | |
| SCHEMBL403826 | 0.75 | TAAR1 (0.47) | GAA | |
| SCHEMBL6370660 | 0.75 | MEN1 (0.32) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997813-B1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2010-05-05 | — | — | EP | disclosed |