Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567348 | 0.74 | LMNA (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL17715571 | 0.66 | HPGD (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL7802339 | 0.66 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL28897709 | 0.65 | HSD17B10 (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL3532 | 0.62 | — | — | |
| Pyrogallol SCHEMBL170157 | 0.62 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL2363598 | 0.61 | CA2 (0.41) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL3993938 | 0.61 | LMNA (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Boric Acid SCHEMBL14940655 | 0.61 | HPGD (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL3567350 | 0.61 | ERN1 (0.48) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |