Water

Water

SCHEMBL3243886

O.O=S(=O)=O.O=S(=O)=O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28313178 0.91
Water SCHEMBL28122856 0.91
SCHEMBL6713 0.89
SCHEMBL27317105 0.89
Hydrogen Sulfide SCHEMBL10979966 0.80
SCHEMBL11798212 0.80
SCHEMBL4731788 0.80
Iodide SCHEMBL4433797 0.80
SCHEMBL10414199 0.80
SCHEMBL16039847 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0913376-B1 Process for the preparation of cyclohexanones MERCK PATENT GMBH (DE) 2002-02-13 EP claimed
US-5081268-A Process for the preparation of oxetanes from 1,3-glycol monosulfates ARCO CHEMICAL TECHNOLOGY, INC. (US) 1992-01-14 US claimed
US-20130345104-A1 POLYISOBUTENYL SULFONATES HAVING LOW POLYDISPERSITY CHEVRON ORONITE COMPANY LLC (US) 2013-12-26 US disclosed
US-8603956-B2 Super overbased polyalkenyl sulfonate and alkylaryl sulfonate composition and process for making the same CHEVRON ORONITE COMPANY LLC (US) 2013-12-10 US disclosed
US-8362153-B2 Have improved low temperature and high temperature viscometric properties; sulfonating polyisobutene and reacting the polyisobutenyl sulfonate with an alkali metal or alkaline earth metal CHEVRON ORONITE COMPANY LLC (US) 2013-01-29 US disclosed
EP-1845149-B1 Super overbased polyalkenyl sulfonate and alkylaryl sulfonate composition and process for making the same CHEVRON ORONITE CO (US) 2010-05-05 EP disclosed
US-7498386-B2 Derivatives of polymers for permanent modification of hydrophobic polymers BASF SE (DE) 2009-03-03 US disclosed
EP-1514881-B1 Improved process for the preparation of stabilized polyalkenyl sulfonic acids CHEVRON ORONITE CO (US) 2008-08-27 EP disclosed
US-20080199420-A1 Cosmetic oil in water emulsion ofamphiphilic polymer with hydrophilic and hydrophobic units formed from polyisobutenes modified with terminal polar groups, emulsifier, oil and water; ethylene oxide-propylene oxide block polymer modified polyisobutenyl succinic anhydride; hydroxylation, epoxidation BASF AKTIENGESELLSCHAFT (DE) 2008-08-21 US disclosed
US-20080146476-A1 POLYISOBUTENYL SULFONATES HAVING LOW POLYDISPERSITY CHEVRON ORONITE COMPANY LLC 2008-06-19 US disclosed
EP-1932859-A2 Polyisobutenyl sulfonates having low polydispersity Chevron Oronite Company LLC (US) 2008-06-18 EP disclosed
EP-1514881-A1 Improved process for the preparation of stabilized polyalkenyl sulfonic acids Chevron Oronite Company LLC (US) 2005-03-16 EP disclosed
US-20040209787-A1 Method of improving the frictional properties of functional fluids CHEVRON ORONITE COMPANY LLC 2004-10-21 US disclosed
US-20040102339-A1 Method of improving the frictional properties of functional fluids CHEVRON ORONITE COMPANY LLC 2004-05-27 US disclosed
US-20040018946-A1 Method of improving the frictional properties of functional fluids CHEVRON ORONITE COMPANY LLC 2004-01-29 US disclosed
EP-1384769-A1 Method of improving the frictional properties of functional fluids Chevron Oronite Company LLC (US) 2004-01-28 EP disclosed
US-6410491-B1 OVERBASED COMPOUNDS; OIL ADDITIVES CHEVRON CHEMICAL COMPANY LLC 2002-06-25 US disclosed
EP-1210378-A2 POLYALKENYL SULFONATES Chevron Oronite Company LLC (US) 2002-06-05 EP disclosed
WO-2001070830-A2 POLYALKENYL SULFONATES CHEVRON ORONITE COMPANY LLC (US) 2001-09-27 WO disclosed
US-5081268-A Process for the preparation of oxetanes from 1,3-glycol monosulfates ARCO CHEMICAL TECHNOLOGY, INC. (US) 1992-01-14 US disclosed