Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.48 |
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247802 | 0.90 | BRAF (0.58) | KDRBRAFCTSCFYN | |
| SCHEMBL3247795 | 0.87 | BRAF (0.46) | KDRBRAFCTSCFYN | |
| SCHEMBL3247799 | 0.86 | ABL1 (0.60) | BRAFCTSC | |
| SCHEMBL3242880 | 0.82 | BRAF (0.54) | KDRBRAFCTSCTEKFYN | |
| SCHEMBL3245277 | 0.82 | ABL1 (0.55) | CTSC | |
| SCHEMBL3245571 | 0.82 | ABL1 (0.59) | CTSC | |
| SCHEMBL3244240 | 0.82 | BRAF (0.69) | BRAFTEKFYNHTR2A | |
| SCHEMBL3235430 | 0.81 | CTSC (0.46) | BRAFCTSCFYN | |
| SCHEMBL3249551 | 0.80 | CTSC (0.45) | KDRBRAFCTSCFYN | |
| SCHEMBL3245525 | 0.80 | AURKA (0.47) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |