⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246557 | 0.80 | — | — | |
| SCHEMBL1640968 | 0.73 | — | — | |
| SCHEMBL1640279 | 0.68 | CBFB (0.34) | — | |
| SCHEMBL3241102 | 0.67 | CBFB (0.34) | — | |
| SCHEMBL1639456 | 0.64 | — | — | |
| SCHEMBL1641262 | 0.64 | HSD17B10 (0.31) | — | |
| SCHEMBL3243506 | 0.64 | — | — | |
| SCHEMBL13636021 | 0.64 | — | — | |
| SCHEMBL7156527 | 0.62 | JAK2 (0.31) | — | |
| SCHEMBL241718 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469001-B1 | Corroles, including chiral derivatives and the use thereof | TECHNION RES & DEV FOUNDATION (IL) | 2010-05-05 | — | — | EP | disclosed |
| EP-1117666-B1 | PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF | TECHNION RES & DEV FOUNDATION (IL) | 2004-12-01 | — | — | EP | disclosed |
| EP-1469001-A1 | Corroles, including chiral derivatives and the use thereof | Technion Research & Development Foundation Limited (IL) | 2004-10-20 | — | — | EP | disclosed |
| US-6541628-B1 | Solvent-free condensation of an aldehyde with a pyrrole derivative to form corroles, salts or complexes | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2003-04-01 | — | — | US | disclosed |