Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718829 | 0.87 | CYP1A2 (0.32) | — | |
| SCHEMBL3243506 | 0.83 | — | — | |
| SCHEMBL1640968 | 0.79 | — | — | |
| SCHEMBL2240992 | 0.74 | RAB9A (0.30) | — | |
| SCHEMBL16924935 | 0.73 | RAB9A (0.32) | — | |
| SCHEMBL3241102 | 0.73 | CBFB (0.34) | — | |
| SCHEMBL1641262 | 0.72 | HSD17B10 (0.31) | — | |
| SCHEMBL1641273 | 0.71 | CCNB2 (0.39) | — | |
| SCHEMBL1640279 | 0.69 | CBFB (0.34) | — | |
| SCHEMBL17366426 | 0.69 | GCGR (0.41) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541628-B1 | Solvent-free condensation of an aldehyde with a pyrrole derivative to form corroles, salts or complexes | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2003-04-01 | — | — | US | disclosed |