Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | LCLAT1 | Q6UWP7 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293705 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1NOTUMNPC1RAB9A | |
| SCHEMBL6449967 | 0.78 | NPC1 (0.60) | KDM4EALDH1A1PIK3R1PIK3CALCLAT1 | |
| SCHEMBL29550378 | 0.75 | PIK3R1 (0.53) | KDM4EALDH1A1PIK3R1PIK3CALCLAT1 | |
| SCHEMBL23567450 | 0.75 | PIK3R1 (0.53) | KDM4EALDH1A1PIK3R1PIK3CALCLAT1 | |
| SCHEMBL13930930 | 0.72 | RAB9A (0.56) | KDM4EALDH1A1LCLAT1NOTUMNPC1 | |
| SCHEMBL12776800 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1LCLAT1NPC1RAB9A | |
| SCHEMBL3251579 | 0.72 | PIK3R1 (0.48) | KDM4EALDH1A1PIK3R1PIK3CALCLAT1 | |
| SCHEMBL5540045 | 0.71 | KDM4E (0.59) | KDM4EALDH1A1NOTUMNPC1RAB9A | |
| SCHEMBL5540037 | 0.71 | KDM4E (0.55) | KDM4EALDH1A1NOTUMNPC1RAB9A | |
| SCHEMBL3980022 | 0.71 | NOTUM (0.52) | KDM4EALDH1A1NOTUMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-10112930-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2017-12-28 | — | — | US | disclosed |
| EP-3233080-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | Monsanto Technology LLC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | disclosed |
| US-9642364-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-9125410-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-06-04 | — | — | US | disclosed |
| EP-2786993-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786994-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786992-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-10112930-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | KDM4E 1933/4885ALDH1A1 3529/4885PIK3R1 1758/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | CYP51A1, MT-CO3, ACOX3 | KDM4E 1960/4885ALDH1A1 1344/4885PIK3R1 2056/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | KDM4E 2135/4885ALDH1A1 2842/4885PIK3R1 2402/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885ALDH1A1 3430/4885PIK3R1 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.