SCHEMBL3246512

SCHEMBL3246512

COC(=O)CSc1ncccc1N

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 5/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
MAPK1 P28482 2/20 0.56
ALOX15 P16050 1/20 0.56
KMT2A Q03164 2/20 0.52
NPSR1 Q6W5P4 5/20 0.52
KDM4E B2RXH2 4/20 0.52
USP2 O75604 2/20 0.52
GAA P10253 1/20 0.52
L3MBTL1 Q9Y468 4/20 0.48
PRNP P04156 5/20 0.46
TSHR P16473 2/20 0.45
PKM P14618 1/20 0.45
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.43
ADORA1 P30542 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3238599 0.83 ALDH1A1 (0.58) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL342862 0.81 RXFP1 (0.56) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL9661173 0.80 PKM (0.68) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL3248057 0.78 ALDH1A1 (0.52) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL3245185 0.77 KMT2A (0.57) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL10118118 0.76 ALDH1A1 (0.53) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL8242315 0.76 RXFP1 (0.50) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL4126057 0.76 HSD17B10 (0.69) RXFP1ALDH1A1HPGDHSD17B10MAPK1
SCHEMBL15227474 0.76 L3MBTL1 (0.62) ALDH1A1HSD17B10KMT2AKDM4EGAA
SCHEMBL15709787 0.74 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1736052-B1 Stem/leaf desiccant SUMITOMO CHEMICAL CO (JP) 2010-04-21 EP disclosed
EP-1736052-B1 Stem/leaf desiccant SUMITOMO CHEMICAL CO (JP) 2010-04-21 EP disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
EP-1397958-B1 STEM/LEAF DESICCANT SUMITOMO CHEMICAL CO (JP) 2007-01-10 EP disclosed
EP-1397958-B1 STEM/LEAF DESICCANT SUMITOMO CHEMICAL CO (JP) 2007-01-10 EP disclosed
EP-1736052-A2 Stem/leaf desiccant Sumitomo Chemical Company, Limited (JP) 2006-12-27 EP disclosed
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-19 US disclosed
US-7115544-B2 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-03 US disclosed
US-7109148-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-19 US disclosed
US-20040152597-A1 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-08-05 US disclosed
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-15 US disclosed
EP-1397958-A1 STEAM/LEAF DESSICANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-17 EP disclosed
WO-2002098227-A1 PLANT GROWTH REGULATORS FOR COTTON HERVEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152597-A1 Plant growth regulators for cotton hervest GHDC, CBR3, CBR1 RXFP1 646/4885ALDH1A1 1703/4885HPGD 2849/4885
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate CPS1, H1-0, H1-3 RXFP1 1116/4885ALDH1A1 389/4885HPGD 3069/4885
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring CPS1, ACACA, ODC1 RXFP1 2624/4885ALDH1A1 57/4885HPGD 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.