Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852838 | 0.98 | CYP2C19 (0.47) | CYP2C19POLBBLMATM | |
| SCHEMBL12852824 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL3248585 | 0.68 | — | — | |
| Acetylthiocholine SCHEMBL400577 | 0.67 | CYP2C19 (0.95) | CYP2C19POLBBLMATM | |
| SCHEMBL12852825 | 0.67 | CYP2C19 (0.32) | CYP2C19POLBBLMATM | |
| Acetylthiocholine SCHEMBL77666 | 0.65 | CYP2C19 (1.00) | CYP2C19POLBBLMATM | |
| SCHEMBL17208778 | 0.64 | CYP2C19 (0.57) | CYP2C19POLBBLMATM | |
| Acetylthiocholine SCHEMBL1276372 | 0.63 | BLM (1.00) | CYP2C19POLBBLMATM | |
| Acetylthiocholine SCHEMBL7172548 | 0.63 | CYP2C19 (0.95) | CYP2C19POLBBLMATM | |
| Acetylthiocholine SCHEMBL4318613 | 0.63 | CYP2C19 (0.95) | CYP2C19POLBBLMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341886-B1 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS | NOVABAY PHARMACEUTICALS INC (US) | 2015-08-26 | — | — | EP | disclosed |
| US-8278482-B2 | Antimicrobial N-chlorinated compositions | NOVABAY PHARMACEUTICALS, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100158818-A1 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158818-A1 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS | NRDC, NHERF1, MPO | CYP2C19 1687/4885POLB 678/4885BLM 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.