Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5413585 | 0.98 | NPBWR1 (0.46) | NPBWR1MCHR1LMNANPSR1TDP1 | |
| SCHEMBL20712771 | 0.84 | NPBWR1 (0.46) | NPBWR1MCHR1LMNANPSR1TDP1 | |
| SCHEMBL3252312 | 0.83 | RAB9A (0.44) | NPBWR1MCHR1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3251404 | 0.79 | RAB9A (0.56) | LMNANPSR1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL2988609 | 0.79 | RAB9A (0.56) | LMNAALDH1A1PKMSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5413922 | 0.78 | RAB9A (0.54) | LMNANPSR1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL6532361 | 0.78 | PTPN1 (0.54) | LMNAALDH1A1SMN1; SMN2RAB9APOLB | |
| Hydrochloric Acid SCHEMBL5414203 | 0.78 | NPBWR1 (0.44) | NPBWR1MCHR1LMNANPSR1TDP1 | |
| SCHEMBL2996492 | 0.75 | MAPK14 (0.56) | NPBWR1MCHR1LMNANPSR1ALDH1A1 | |
| SCHEMBL1753026 | 0.75 | NPC1 (0.63) | NPSR1ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685091-B1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | PROCTER & GAMBLE (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-1718601-B1 | (3,5-DIAMINOPHENYL)(2,4-DIHYDROXYPHENYL)METHANONE AND ITS ACID ADDUCTS, METHOD FOR THE PRODUCTION OF THE LATTER AND USE OF SAID COMPOUNDS FOR COLOURING FIBRES | WELLA AG (DE) | 2009-03-25 | — | — | EP | disclosed |
| US-7455697-B2 | (3,5-diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | WELLA AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-7361198-B2 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | WELLA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| US-20070180629-A1 | (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | Wella GmbH (DE) | 2007-08-09 | — | — | US | disclosed |
| US-7195649-B2 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | WELLA AG (DE) | 2007-03-27 | — | — | US | disclosed |
| US-7195649-B2 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | WELLA AG (DE) | 2007-03-27 | — | — | US | disclosed |
| EP-1718601-A1 | (3,5-DIAMINOPHENYL)(2,4-DIHYDROXYPHENYL)METHANONE AND ITS ACID ADDUCTS, METHOD FOR THE PRODUCTION OF THE LATTER AND USE OF SAID COMPOUNDS FOR COLOURING FIBRES | Wella Aktiengesellschaft (DE) | 2006-11-08 | — | — | EP | disclosed |
| EP-1636219-B1 | NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS | WELLA AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-20060183781-A1 | Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers | WELLA AG (DE) | 2006-08-17 | — | — | US | disclosed |
| EP-1685091-A1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | Wella Aktiengesellschaft (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20060047172-A1 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | Wella GmbH (DE) | 2006-03-02 | — | — | US | disclosed |
| WO-2005080315-A1 | (3,5-DIAMINOPHENYL)(2,4-DIHYDROXYPHENYL)METHANONE AND ITS ACID ADDUCTS, METHOD FOR THE PRODUCTION OF THE LATTER AND USE OF SAID COMPOUNDS FOR COLOURING FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005051889-A1 | M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047172-A1 | M-diaminobenzenes, their acid adducts and the use thereof in colorants | DDT, NQO1, MDH2 | NPBWR1 3544/4885MCHR1 469/4885LMNA 1823/4885 |
| US-20060183781-A1 | Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers | KRT18, CBR3, CDC73 | NPBWR1 3445/4885MCHR1 3845/4885LMNA 581/4885 |
| US-20070180629-A1 | (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | GRHPR, MB, COX5B | NPBWR1 2866/4885MCHR1 8/4885LMNA 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.