Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250779 | 0.91 | PKM (0.34) | PKMLMNAMAPTALDH1A1HPGD | |
| SCHEMBL3249412 | 0.90 | — | — | |
| SCHEMBL3241908 | 0.87 | — | — | |
| SCHEMBL3251464 | 0.87 | LMNA (0.36) | PKMLMNAMAPTALDH1A1HPGD | |
| SCHEMBL3255160 | 0.85 | MAPT (0.38) | LMNAMAPTALDH1A1HPGD | |
| SCHEMBL3249777 | 0.83 | ALOX5AP (0.33) | — | |
| SCHEMBL3252606 | 0.81 | ALDH1A1 (0.36) | LMNAMAPTALDH1A1HPGD | |
| SCHEMBL3245465 | 0.81 | ALDH1A1 (0.36) | LMNAMAPTALDH1A1HPGD | |
| SCHEMBL3254901 | 0.80 | KDM4E (0.38) | LMNAMAPTALDH1A1HPGD | |
| SCHEMBL3251021 | 0.80 | MAPT (0.32) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |