Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660983 | 0.84 | HDAC1 (0.62) | HDAC1HDAC6LTA4HCYP11B1CYP11B2 | |
| SCHEMBL30227032 | 0.81 | HDAC1 (0.58) | HDAC1HDAC6LTA4HCYP11B1CYP11B2 | |
| SCHEMBL31229158 | 0.77 | CYP11B1 (0.62) | LTA4HCYP11B1CYP11B2TNFKDM4C | |
| SCHEMBL12472644 | 0.77 | HDAC6 (1.00) | HDAC1HDAC6MET | |
| SCHEMBL28290149 | 0.76 | CYP11B1 (0.53) | HDAC1HDAC6CYP11B1CYP11B2TNF | |
| SCHEMBL7138434 | 0.76 | LTA4H (1.00) | LTA4HLMNAKMT2A | |
| SCHEMBL12472198 | 0.76 | HDAC6 (0.72) | HDAC1HDAC6LTA4HCYP11B1CYP11B2 | |
| SCHEMBL7815689 | 0.75 | CYP11B1 (0.51) | CYP11B1CYP11B2TNFKDM4CADORA2A | |
| 9-Benzyl-9H-Purine SCHEMBL434620 | 0.74 | HDAC1 (0.61) | HDAC1HDAC6LTA4HCYP11B1CYP11B2 | |
| SCHEMBL48336 | 0.74 | ADORA2A (0.47) | HDAC1HDAC6LTA4HADORA2API4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728757-B1 | Process for producing purine derivatives | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | claimed |
| US-6252075-B1 | REACTING A 7-BENZYLPURINE COMPOUND WITH A 1,3-DIOXEPANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2001-06-26 | — | — | US | claimed |
| US-5942617-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1999-08-24 | — | — | US | claimed |
| US-5831092-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1998-11-03 | — | — | US | claimed |
| EP-0827960-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1998-03-11 | — | — | EP | claimed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | claimed |
| JP-8291175-A | — | — | None | — | — | JP | disclosed |
| JP-10120682-A | — | — | None | — | — | JP | disclosed |
| EP-1501851-B1 | PROCESS FOR PREPARING OLIGONUCLEOTIDES | NITTO DENKO AVECIA INC (US) | 2013-02-13 | — | — | EP | disclosed |
| US-8093397-B2 | Activators for oligonucleotide synthesis | AVECIA BIOTECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| EP-1575975-B1 | PROCESS FOR THE PREPARATION OF OLIGONUCLEOTIDES | AVECIA BIOTECHNOLOGY INC (US) | 2010-10-27 | — | — | EP | disclosed |
| US-7635772-B2 | Process for the preparation of oligonucleotides | AVECIA BIOTECHNOLOGY INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-20090085006-A1 | Activators for oligonucleotide synthesis | AVECIA BIOTECHNOLOGY, INC. (US) | 2009-04-02 | — | — | US | disclosed |
| US-5942617-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5831092-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1998-11-03 | — | — | US | disclosed |
| JP-H10120682-A | PRODUCTION OF PURINE DERIVATIVE | AJINOMOTO CO INC | 1998-05-12 | — | — | JP | disclosed |
| EP-0827960-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1998-03-11 | — | — | EP | disclosed |
| EP-0827960-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1998-03-11 | — | — | EP | disclosed |
| JP-H08291175-A | PRODUCTION OF PURINE DERIVATIVE | AJINOMOTO CO INC | 1996-11-05 | — | — | JP | disclosed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090085006-A1 | Activators for oligonucleotide synthesis | MED12, ORC3, NOP2 | HDAC1 963/4885HDAC6 2790/4885LTA4H 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.