Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634473 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PTGS1ADRA2BTDP1NPC1 | |
| SCHEMBL3786504 | 0.86 | FYN (0.45) | ALDH1A1PTGS1ADRA2BTDP1NPC1 | |
| SCHEMBL2212731 | 0.85 | ALDH1A1 (0.52) | ALDH1A1PTGS1ADRA2BTDP1NPC1 | |
| SCHEMBL31607623 | 0.85 | ALDH1A1 (0.52) | ALDH1A1PTGS1ADRA2BTDP1NPC1 | |
| SCHEMBL27938882 | 0.85 | ABL1 (0.50) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28929369 | 0.84 | ALDH1A1 (0.43) | ALDH1A1PTGS1ADRA2BTDP1NPC1 | |
| SCHEMBL4965451 | 0.83 | NCOA1 (0.53) | ALDH1A1TDP1RAB9AMAPK1MAPT | |
| SCHEMBL3790127 | 0.83 | FYN (0.50) | ALDH1A1PTGS1ADRA2BNPC1RAB9A | |
| SCHEMBL28184418 | 0.82 | CYP3A4 (0.54) | ALDH1A1MAPTKMT2ACYP1A2CYP3A4 | |
| Methylamine SCHEMBL28363123 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PTGS1ADRA2BTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101040028-B | Photocrosslinkable materials | ROLIC AG | 2012-03-28 | — | — | CN | claimed |
| CN-101040028-A | Photocrosslinkable materials | ROLIC AG (CH) | 2007-09-19 | — | — | CN | claimed |
| US-11555012-B2 | ACLY inhibitors and uses thereof | Nimbus Artemis, Inc. (US) | 2023-01-17 | — | — | US | disclosed |
| CN-110627721-B | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-110128570-B | Dendritic photosensitizer containing benzidine-based fragment, synthetic method and application | 郑州工程技术学院 | 2021-06-15 | — | — | CN | disclosed |
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. | 2020-05-14 | — | — | US | disclosed |
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. | 2020-05-14 | — | — | US | disclosed |
| CN-110627721-A | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2019-12-31 | — | — | CN | disclosed |
| CN-105017302-B | Bis- (S, S- dioxo-dibenzothiophenes) and 5-membered ring compounds and the preparation method and application thereof | 华南理工大学 | 2019-06-18 | — | — | CN | disclosed |
| CN-109804306-A | Light orientation copolymer material | 罗利克技术有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-108912011-A | Light arrangement material | 罗立克科技股份公司 | 2018-11-30 | — | — | CN | disclosed |
| US-7396958-B2 | Sulphonamide derivatives, their preparation and their therapeutic application | SANOFI AVENTIS (FR) | 2008-07-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-101090892-A | Sulfonamide derivatives, process for their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | CN | disclosed |
| CN-101040028-A | Photocrosslinkable materials | ROLIC AG (CH) | 2007-09-19 | — | — | CN | disclosed |
| US-20070185136-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2007-08-09 | — | — | US | disclosed |
| EP-1776347-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Sanofi-Aventis (FR) | 2007-04-25 | — | — | EP | disclosed |
| US-20060152143-A1 | White-emitting compounds, process for the production thereof, and white-emitting devices | HIROSE ENGINEERING CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1650208-A1 | WHITE-EMITTING COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND WHITE-EMITTING DEVICES | HIROSE ENGINEERING CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
| WO-2006024779-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | ALDH1A1 1455/4885PTGS1 3863/4885ADRA2B 4461/4885 |
| US-11555012-B2 | ACLY inhibitors and uses thereof | ACLY, ATP5ME, ATP5MG | ALDH1A1 1455/4885PTGS1 3863/4885ADRA2B 4461/4885 |
| US-20060152143-A1 | White-emitting compounds, process for the production thereof, and white-emitting devices | IWS1, WNT1, CYP1A1 | ALDH1A1 39/4885PTGS1 1266/4885ADRA2B 1732/4885 |
| US-20070185136-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | HCRTR2, GIPR, SSTR2 | ALDH1A1 2179/4885PTGS1 4726/4885ADRA2B 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.