SCHEMBL3256514

SCHEMBL3256514

NCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.72
▸ CA12 O43570 6/20 0.66
▸ CA1 P00915 6/20 0.66
▸ CA2 P00918 6/20 0.66
▸ CA9 Q16790 6/20 0.66
▸ PKM P14618 2/20 0.65
▸ MEN1 O00255 1/20 0.65
▸ ABL1 P00519 1/20 0.65
▸ LMNA P02545 1/20 0.65
▸ IDE P14735 1/20 0.65
▸ MAPK1 P28482 1/20 0.65
▸ KMT2A Q03164 1/20 0.65
▸ RIN1 Q13671 1/20 0.65
▸ L3MBTL1 Q9Y468 1/20 0.65
▸ HLCS P50747 3/20 0.57
▸ F2 P00734 1/20 0.57
▸ PRSS1 P07477 1/20 0.57
▸ PRSS2 P07478 1/20 0.57
▸ PRSS3 P35030 1/20 0.57
▸ TPSAB1 Q15661 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26598596 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL30821562 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL10140274 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL25014977 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL10000338 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL24420141 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
SCHEMBL15895090 1.00 TDP1 (0.72) TDP1CA12CA1CA2CA9
Ethylenediamine SCHEMBL16679417 0.99 TDP1 (0.70) TDP1CA12CA1CA2CA9
Bromide SCHEMBL2678585 0.99 TDP1 (0.70) TDP1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL8147632 0.99 TDP1 (0.70) TDP1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119986004-A Milligram-grade drug-resistant antibody detection method and detection kit 北京新艾进生物科技有限公司 2025-05-13 — — CN claimed
CN-107849089-B Solution phase synthesis and crystallization of beta-turn cyclic peptidomimetic salts 米梅奥亨制药公司 2022-07-05 — — CN claimed
CN-111269164-B Ketone compound, preparation method and application thereof, and method for site-directed modification of protein containing cysteine residues or disulfide bonds 南开大学 2021-11-02 — — CN claimed
EP-4065619-B1 BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-05-27 — — EP disclosed
CN-116773831-B Method, reagent and kit for measuring sterols in lipoproteins 希森美康株式会社 2026-05-15 — — CN disclosed
EP-4246147-B1 METHOD FOR MEASURING STEROL IN LIPOPROTEIN, AND REAGENT FOR MEASURING STEROL IN LIPOPROTEIN SYSMEX CORP (JP) 2026-05-06 — — EP disclosed
US-12528824-B2 Biotin-containing monomers and articles formed therefrom Thermo Fisher Bioprocessing Inc. (US) 2026-01-20 — — US disclosed
US-20250381168-A1 VLA4 INHIBITORS AND USES THEREOF WASHINGTON UNIVERSITY ST LOUIS (US) 2025-12-18 — — US disclosed
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-12-04 — — US disclosed
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2025-11-13 — — US disclosed
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-11-06 — — US disclosed
US-20020187249-A1 Process for the production of surface-functionalized supports that serve as starting materials for microarrays used for immobilizing biomolecules PLUSTER WILHELM (US) 2002-12-12 — — US disclosed
US-6462041-B1 ACTIVATORS OF CASPASE CASCADE; TREATING, PREVENTING OR AMELIORATING NEOPLASIA AND CANCER CYTOVIA, INC. 2002-10-08 — — US disclosed
EP-1204488-A1 METHOD FOR PRODUCING SURFACE-FUNCTIONALIZED SUPPORTS USED AS STARTING PRODUCTS FOR MICROARRAYS, FOR IMMOBILIZING BIOMOLECULES EPPENDORF AG (DE) 2002-05-15 — — EP disclosed
EP-1180991-A2 GAMBOGIC ACID, ANALOGS AND DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS Cytovia, Inc. (US) 2002-02-27 — — EP disclosed
WO-2001094032-A1 METHOD FOR PRODUCING SURFACE-FUNCTIONALIZED SUPPORTS USED AS STARTING PRODUCTS FOR MICROARRAYS, FOR IMMOBILIZING BIOMOLECULES EPPENDORF AG (DE) 2001-12-13 — — WO disclosed
WO-2000044216-A2 GAMBOGIC ACID, ANALOGS AND DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS CYTOVIA INC (US) 2000-08-03 — — WO disclosed
US-6030846-A Homogeneous assays using avidin-binding azo reagents DADE BEHRING INC. (US) 2000-02-29 — — US disclosed
US-5612221-A Avidin-binding fluorescing and quenching reagent for use in homogeneous assays DADE CHEMISTRY SYSTEMS INC. (US) 1997-03-18 — — US disclosed
US-5536820-A Avidin-binding azo reagents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES SORT1, SCARB1, LAMP1 TDP1 2734/4885CA12 4066/4885CA1 4441/4885
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION CAPRIN1, NOS1, NCBP1 TDP1 975/4885CA12 2469/4885CA1 828/4885
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER NSUN3, AGO2, ZFR TDP1 1666/4885CA12 3388/4885CA1 3908/4885
US-12528824-B2 Biotin-containing monomers and articles formed therefrom PBRM1, ICAM1, EPCAM TDP1 3688/4885CA12 2120/4885CA1 3095/4885
US-20250381168-A1 VLA4 INHIBITORS AND USES THEREOF CXCR4, SDF4, ITGB4 TDP1 3968/4885CA12 2667/4885CA1 3154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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