Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 8/20 | 0.44 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | INPP5B | P32019 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25222316 | 0.74 | INPPL1 (0.59) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL7594504 | 0.70 | INPPL1 (0.44) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL574460 | 0.68 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL25273082 | 0.68 | CYP2A6 (0.46) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL30023648 | 0.67 | INPPL1 (0.54) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL258268 | 0.67 | INPPL1 (0.54) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL7591865 | 0.67 | INPPL1 (0.50) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL10751352 | 0.66 | INPPL1 (0.46) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL25259132 | 0.66 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL28200081 | 0.66 | ALDH1A1 (0.33) | INPPL1INPP5AAKT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100000881-A1 | Electrochemical detection of nucleic acid hybridization | NORTH CAROLINA STATE UNIVERSITY | 2010-01-07 | — | — | US | disclosed |
| US-20050191651-A1 | Temperature-jump enhanced electrochemical detection of nucleic acid hybridization | NORTH CAROLINA STATE UNIVERSITY | 2005-09-01 | — | — | US | disclosed |
| WO-2005042783-A1 | TEMPERATURE-JUMP ENHANCED ELECTROCHEMICAL DETECTION OF NUCLEIC ACID HYBRIDIZATION | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005042785-A1 | ELECTROCHEMICAL DETECTION OF NUCLEIC ACID HYBRIDIZATION | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-05-12 | — | — | WO | disclosed |
| US-4830959-A | Electrochemical enzymic assay procedures | MEDISENSE, INC. (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0223541-A2 | Electrochemical enzymic assay procedures | MediSense, Inc. (US) | 1987-05-27 | — | — | EP | disclosed |