Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693045 | 0.98 | EPHX2 (0.66) | EPHX2MEN1ALDH1A1MAPTHTT | |
| SCHEMBL13479840 | 0.87 | EPHX2 (0.50) | EPHX2MEN1ALDH1A1MAPTHTT | |
| SCHEMBL3260176 | 0.86 | EPHX2 (0.51) | EPHX2MEN1ALDH1A1MAPTHTT | |
| SCHEMBL2925051 | 0.83 | EPHX2 (0.49) | EPHX2MEN1ALDH1A1MAPTHTT | |
| SCHEMBL6926505 | 0.81 | EPHX2 (0.52) | EPHX2MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL15686015 | 0.81 | EPHX2 (0.98) | EPHX2 | |
| SCHEMBL672426 | 0.81 | PSIP1 (0.48) | EPHX2ALDH1A1MAPTATMCA12 | |
| Phenolsulphonic Acid SCHEMBL27522931 | 0.80 | EPHX2 (0.51) | EPHX2MEN1ALDH1A1MAPTHTT | |
| SCHEMBL8778827 | 0.80 | KEAP1 (0.60) | EPHX2ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL15643851 | 0.80 | EPHX2 (1.00) | EPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223185-A1 | CHEMILUMINESCENT MATERIALS AND METHOD OF MAKING SAME | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-08-09 | — | — | US | disclosed |
| US-10040993-B1 | Chemiluminescent materials and method of making same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-08-07 | — | — | US | disclosed |
| EP-1748995-B1 | ARYLSULFONYL BENZODIOXANES USEFUL FOR MODULATION THE 5-HT6 RECEPTOR, THE 5-HT2ARECEPTOR OR BOTH | HOFFMANN LA ROCHE (CH) | 2010-02-24 | — | — | EP | disclosed |
| US-7368567-B2 | Arylsulfonyl benzodioxanes, benzoxazines and benzothiazines as 5-HT6 antagonists | ROCHE PALO ALTO LLC (US) | 2008-05-06 | — | — | US | disclosed |
| EP-1748995-A1 | ARYLSULFONYL BENZODIOXANES USEFUL FOR MODULATION THE 5-HT6 RECEPTOR, THE 5-HT2ARECEPTOR OR BOTH | F. Hoffmann-La Roche AG (CH) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005105776-A1 | ARYLSULFONYL BENZODIOXANES USEFUL FOR MODULATION THE 5-HT6 RECEPTOR, THE 5-HT2ARECEPTOR OR BOTH | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-10 | — | — | WO | disclosed |
| US-20050250943-A1 | Arylsulfonyl benzodioxanes, benzoxazines and benzothiazines as 5-HT6 antagonists | ROCHE PALO ALTO LLC | 2005-11-10 | — | — | US | disclosed |
| US-6790569-B2 | VARIATIONS IN PHOTOSENSITIVITY | EASTMAN KODAK COMPANY | 2004-09-14 | — | — | US | disclosed |
| EP-1295172-A2 | COLOR PHOTOTHERMOGRAPHIC ELEMENTS COMPRISING PHENOLIC THERMAL SOLVENTS | EASTMAN KODAK COMPANY (US) | 2003-03-26 | — | — | EP | disclosed |
| US-20020025498-A1 | Color photothermographic elements comprising phenolic thermal solvents | YANG XIQIANG (US) | 2002-02-28 | — | — | US | disclosed |
| WO-2001096944-A2 | COLOR PHOTOTHERMOGRAPHIC ELEMENTS COMPRISING PHENOLIC THERMAL SOLVENTS | EASTMAN KODAK COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| US-5843618-A | Hydrogen bond donating/accepting thermal solvents for image separation systems | EASTMAN KODAK COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5665675-A | THERMAL RECORDING MEDIUM | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| US-5480760-A | SULFONAMIDE THERMAL SOLVENT FOR IMPROVED DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5480761-A | CHROMOGENIC PHOTOGRAPHIC ELEMENTS WITH DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5468587-A | Water developable chromogenic photographic heat transferable non-aqueous dye diffusion transfer photographic element | EASTMAN KODAK COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0325231-A2 | Heat-sensitive recording material | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0289041-A2 | Thermosensitive recording sheet | JUJO PAPER CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250943-A1 | Arylsulfonyl benzodioxanes, benzoxazines and benzothiazines as 5-HT6 antagonists | HTR6, HTR7, HTR1F | EPHX2 1736/4885MEN1 2318/4885ALDH1A1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.