Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557551 | 0.83 | FFAR2 (0.46) | MAPTGAARAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL3257731 | 0.83 | L3MBTL1 (0.41) | ADORA1HTTL3MBTL1MAPTHSD17B10 | |
| SCHEMBL3564741 | 0.81 | CYP1A2 (0.51) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL3244773 | 0.80 | ALDH1A1 (0.35) | ADORA1HSD17B10KDM5AMEN1KMT2A | |
| SCHEMBL3256189 | 0.76 | MEN1 (0.47) | ADORA1HTTMEN1KMT2AHPGD | |
| SCHEMBL3556396 | 0.75 | ALOX15 (0.46) | ADORA1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL3257632 | 0.75 | ALOX15 (0.46) | ADORA1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL3260122 | 0.75 | CETP (0.39) | ADORA1KDM5ANPY2R | |
| SCHEMBL3256718 | 0.74 | CCNA2 (0.49) | CCNA2CDK2CCNA1 | |
| SCHEMBL13827683 | 0.73 | HTT (0.42) | ADORA1HTTL3MBTL1MAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689721-B1 | AMINOPYRAZOLE DERIVATIVES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2010-07-14 | — | — | EP | claimed |