Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | DBH | P09172 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458008 | 0.94 | CYP2A6 (0.65) | CYP2A6KDM4EGAADBHRECQL | |
| SCHEMBL12418686 | 0.90 | KDM4E (0.63) | CYP2A6KDM4EGAADBHRECQL | |
| SCHEMBL8745697 | 0.85 | KDM4E (0.53) | CYP2A6KDM4EGAADBHRECQL | |
| SCHEMBL19090508 | 0.82 | KDM4E (0.55) | CYP2A6KDM4EGAADBHRECQL | |
| SCHEMBL759389 | 0.82 | CES2 (0.61) | KDM4EGAADBHRECQLTDP1 | |
| SCHEMBL5020197 | 0.81 | KDM4E (0.69) | CYP2A6KDM4EGAADBHRECQL | |
| SCHEMBL12317627 | 0.81 | KDM4E (0.58) | KDM4EGAADBHRECQLCYP1A2 | |
| SCHEMBL16811768 | 0.81 | ALDH1A1 (0.54) | KDM4EGAADBHRECQLCYP1A2 | |
| SCHEMBL10458095 | 0.79 | KDM4E (0.52) | KDM4EGAADBHRECQLCYP1A2 | |
| SCHEMBL585256 | 0.79 | ALDH1A1 (0.56) | KDM4EGAADBHRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | claimed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | claimed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | claimed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | claimed |
| US-8987315-B2 | Metalloenzyme inhibitor compounds | INNOCRIN PHARMACEUTICALS, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-20120309800-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-RE41136-E1 | Process for preparing 2,6-dialkylnaphthalene | KOBE STEEL, LTD (JP) | 2010-02-16 | — | — | US | disclosed |
| US-RE39222-E1 | Process for preparing 2,6-dialkylnaphthalene | KOBE STEEL, LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| EP-1023250-B1 | PROCESS FOR PREPARING 2,6-DIALKYLNAPHTHALENE | KOBE STEEL LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| EP-1165473-B1 | PROCESS FOR PREPARING 2,6-DIALKYLNAPHTALENE | KOBE STEEL LTD (JP) | 2004-06-23 | — | — | EP | disclosed |
| EP-0812813-B1 | Process for preparing dialkylnaphthalenes | KOBE STEEL LTD (JP) | 2002-03-20 | — | — | EP | disclosed |
| EP-1023250-A4 | PROCESS FOR PREPARING 2,6-DIALKYLNAPHTHALENE | KOBE STEEL LTD (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0517979-A1 | Process for producing aromatic acylation product | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4967011-A | IN THE PRESENCE OF BENZENE, TOLUENE OR CHLOROBENZENE AND PENTANE, HEXANE OR CYCLOHEXANE | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0361479-A2 | Process for decomposing aromatic acylated compound.HF-BF3 complex | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-04-04 | — | — | EP | disclosed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0212480-A1 | Process for the production of 6-acyl-2-alkyl-naphthalene | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309800-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | CYP2A6 619/4885KDM4E 3322/4885GAA 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.