Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.41 |
| ▸ | FDPS | P14324 | 11/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439721 | 0.81 | GGPS1 (0.39) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL4457163 | 0.78 | TSHR (0.57) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL16685436 | 0.70 | TSHR (0.47) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL28571235 | 0.70 | TSHR (0.47) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL30381193 | 0.70 | TSHR (0.47) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL7189663 | 0.70 | TSHR (0.47) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL8470352 | 0.70 | TSHR (0.47) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL2122903 | 0.69 | TSHR (0.44) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL15847082 | 0.69 | TSHR (0.44) | GGPS1SMPD1FDPSTSHRTHRB | |
| SCHEMBL959827 | 0.69 | TSHR (0.44) | GGPS1SMPD1FDPSTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674938-B2 | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-09 | — | — | US | disclosed |
| US-20080249177-A1 | AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. | 2008-10-09 | — | — | US | disclosed |
| EP-1593666-B1 | AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1436263-B1 | A PROCESS FOR PREPARING BETA-KETOESTER COMPOUND | LG LIFE SCIENCES LTD (KR) | 2007-09-19 | — | — | EP | disclosed |
| US-6987199-B2 | Process for preparing beta-ketoester compound | LG LIFE SCIENCES LTD. (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1436263-A4 | A PROCESS FOR PREPARING BETA-KETOESTER COMPOUND | LG LIFE SCIENCES LTD (KR) | 2005-11-02 | — | — | EP | disclosed |
| US-20040249163-A1 | Process for preparing beta-ketoester compound | LG CHEM, LTD. (KR) | 2004-12-09 | — | — | US | disclosed |
| EP-1436263-A1 | A PROCESS FOR PREPARING BETA-KETOESTER COMPOUND | LG Life Sciences Ltd. (KR) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033469-A1 | A PROCESS FOR PREPARING BETA-KETOESTER COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249177-A1 | AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF | ADRB3, ADRA2C, ADRA1A | GGPS1 3290/4885SMPD1 3945/4885FDPS 4808/4885 |
| US-20040249163-A1 | Process for preparing beta-ketoester compound | CYP51A1, CYP46A1, HSD17B7 | GGPS1 55/4885SMPD1 1269/4885FDPS 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.