Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261384 | 0.86 | LMNA (0.57) | PDE3BPDE3AMAPTNPC1RAB9A | |
| SCHEMBL11553029 | 0.79 | ALOX5 (0.54) | SMN1; SMN2PDE3BPDE3AALOX5KDM4E | |
| SCHEMBL1659952 | 0.78 | CYP1A2 (0.49) | SMN1; SMN2MAPTKMT2ACA12CA1 | |
| SCHEMBL13495321 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7005248 | 0.75 | RAB9A (0.54) | SMN1; SMN2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL25382643 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7006136 | 0.73 | RAB9A (0.52) | SMN1; SMN2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL3262663 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9696908 | 0.73 | ALOX5 (0.56) | MAPTKMT2AALOX5KDM4EPTGES | |
| SCHEMBL16345116 | 0.72 | KMT2A (0.62) | SMN1; SMN2PDE3BPDE3AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |