Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.38 |
| ▸ | PON1 | P27169 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377345 | 0.81 | PTPN1 (0.50) | NPSR1HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL15842309 | 0.79 | HPGD (0.53) | NPSR1HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL11621088 | 0.77 | CA9 (0.56) | NPSR1LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL11584039 | 0.77 | NPSR1 (0.47) | NPSR1HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL17942935 | 0.77 | HSD17B3 (0.56) | NPSR1LMNAPPARGNCOA2RXFP1 | |
| SCHEMBL7129765 | 0.75 | MAOB (0.56) | NPSR1LMNAPPARGNCOA2RXFP1 | |
| SCHEMBL14405907 | 0.74 | MAOB (0.60) | NPSR1LMNAPPARGNCOA2RXFP1 | |
| SCHEMBL530998 | 0.74 | GPR35 (0.68) | HPGDKDM4EALDH1A1MAOBGPR35 | |
| SCHEMBL1861098 | 0.73 | HSD17B3 (0.60) | NPSR1RXFP1HPGDKDM4EALDH1A1 | |
| SCHEMBL893041 | 0.73 | KDM4E (0.61) | NPSR1LMNAPPARGNCOA2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | CLSPN, CLTC, HACD3 | NPSR1 3458/4885LMNA 1910/4885PPARG 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.