Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11505235 | 0.78 | — | — | |
| SCHEMBL1897824 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30792004 | 0.74 | GOT1 (0.46) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL1456807 | 0.74 | GOT1 (0.46) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL29442588 | 0.74 | GOT1 (0.46) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL498897 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29044100 | 0.73 | CYP3A4 (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12608094 | 0.72 | MEN1 (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30596386 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL36011 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554361-B1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | DU PONT (US) | 2010-03-17 | — | — | EP | claimed |
| US-7090929-B2 | Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-15 | — | — | US | claimed |
| EP-1554361-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2005-07-20 | — | — | EP | claimed |
| US-20040072018-A1 | Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions | LG CHEM, LTD. (KR) | 2004-04-15 | — | — | US | claimed |
| WO-2004015025-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
| US-9812315-B2 | Treating solution for electronic parts, and process for producing electronic parts | FINE POLYMERS CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-9249154-B2 | Compounds and therapeutic use thereof for protein kinase inhibition | WU ZHANGGUI (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150279654-A1 | TREATING SOLUTION FOR ELECTRONIC PARTS, AND PROCESS FOR PRODUCING ELECTRONIC PARTS | FINE POLYMERS CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20130143887-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USE THEREOF FOR PROTEIN KINASE INHIBITION | WU ZHANGGUI (US) | 2013-06-06 | — | — | US | disclosed |
| US-8318740-B2 | Compounds for protein kinase inhibition | WU ZHANGGUI (US) | 2012-11-27 | — | — | US | disclosed |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | WU ZHANGGUI | 2009-11-05 | — | — | US | disclosed |
| US-20060235021-A1 | Phenylpyridazine derivatives as ligands for gaba receptors | MERCK SHARP & DOHME LTD. (GB) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235021-A1 | Phenylpyridazine derivatives as ligands for gaba receptors | GABRA5, GABRA2, GABRA3 | KDM4E 3010/4885ALDH1A1 236/4885HPGD 996/4885 |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | CHEK2, CHEK1, PLK1 | KDM4E 1966/4885ALDH1A1 3639/4885HPGD 2757/4885 |
| US-20130143887-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USE THEREOF FOR PROTEIN KINASE INHIBITION | CHEK2, CHEK1, PLK1 | KDM4E 1966/4885ALDH1A1 3639/4885HPGD 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.