SCHEMBL3263071

SCHEMBL3263071

CCOc1n[nH]c(C(F)(F)F)c1I

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17156157 0.73 LRRK2 (0.46) LRRK2
SCHEMBL13495080 0.71 L3MBTL1 (0.55) LRRK2
SCHEMBL13495143 0.69 SLC5A2 (0.52)
SCHEMBL3465290 0.69 DYRK1A (0.32)
SCHEMBL3263505 0.67 LRRK2 (0.40) LRRK2
SCHEMBL3263148 0.66 LRRK2 (0.46) LRRK2
SCHEMBL2374709 0.61 ABCC8 (0.56)
SCHEMBL13495301 0.61 ALPL (0.37) LRRK2
SCHEMBL18833366 0.60 CDK1 (0.38)
SCHEMBL16402355 0.59 LRRK2 (0.44) LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010015657-A2 NEW ALKOXYPYRAZOLES INSTITUT PASTEUR (FR) 2010-02-11 WO disclosed
WO-2010015657-A2 NEW ALKOXYPYRAZOLES INSTITUT PASTEUR (FR) 2010-02-11 WO disclosed
EP-2151433-A1 Alkoxypyrazoles and the process for their preparation Institut Pasteur (FR) 2010-02-10 EP disclosed