Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443885 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA9MEN1 | |
| Cyclohexane SCHEMBL16592775 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA9MEN1 | |
| Methyl Alcohol SCHEMBL18335383 | 0.91 | ALDH1A1 (0.41) | ALDH1A1CA1CA2CA9MEN1 | |
| Cyclohexane SCHEMBL2770764 | 0.91 | ALDH1A1 (0.41) | ALDH1A1CA1CA2CA9MEN1 | |
| SCHEMBL15068452 | 0.89 | CA1 (0.46) | ALDH1A1CA1CA2CA9MEN1 | |
| SCHEMBL15584 | 0.89 | — | — | |
| Cyclohexane SCHEMBL1525976 | 0.88 | TSHR (0.50) | ALDH1A1CA1CA2CA9MEN1 | |
| Ethylene Glycol SCHEMBL5612529 | 0.88 | ALDH1A1 (0.39) | ALDH1A1CA1CA2CA9MEN1 | |
| SCHEMBL3265050 | 0.85 | — | — | |
| SCHEMBL11244035 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | claimed |
| EP-2474524-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | claimed |
| EP-2474526-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | claimed |
| EP-2474523-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | claimed |
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| EP-2474525-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-2474523-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20180339070-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-11-29 | — | — | US | disclosed |
| US-20180339070-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-11-29 | — | — | US | disclosed |
| US-10010631-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010631-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A3 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING INC (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| EP-0042404-A1 | TERTIARY DI-(BETA-HYDROXY ORGANO)AMINE OXIDES AND THEIR PREPARATION | SHEREX CHEMICAL COMPANY, INC. (US) | 1981-12-30 | — | — | EP | disclosed |
| WO-1981001847-A1 | TERTIARY DI-(BETA-HYDROXY ORGANO)AMINE OXIDES AND THEIR PREPARATION | SHEREX CHEM (US) | 1981-07-09 | — | — | WO | disclosed |
| US-4275236-A | Tertiary di-(β-hydroxy organo) amine oxides and their preparation | SHEREX CHEMICAL COMPANY, INC. (US) | 1981-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010631-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | ALDH1A1 798/4885CA1 3758/4885CA2 3921/4885 |
| US-20180339070-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | ALDH1A1 798/4885CA1 3758/4885CA2 3921/4885 |
| US-11241509-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | ALDH1A1 662/4885CA1 3856/4885CA2 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.