Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263411 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBL3MBTL1FKBP1AFKBP4 | |
| SCHEMBL6949518 | 0.90 | GSK3A (0.41) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL563087 | 0.82 | GSK3A (0.41) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL563088 | 0.82 | GSK3A (0.41) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL563774 | 0.82 | APEX1 (0.54) | L3MBTL1FKBP1ACYP1A2MEN1KMT2A | |
| SCHEMBL9203370 | 0.77 | APEX1 (0.58) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL9203374 | 0.77 | APEX1 (0.58) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL9301450 | 0.77 | APEX1 (0.58) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL9301677 | 0.74 | GSK3A (0.41) | ALDH1A1FKBP1AFKBP4FKBP5GSK3A | |
| SCHEMBL10681074 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBL3MBTL1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102615-B2 | N-Carbamoylmethy1-4-(R)-phenyl-2-pyrrolidinone, method of its preparation and pharmaceutical use | Joint Stock Company (JSC) “OLAINFARM” (LV) | 2015-08-11 | — | — | US | claimed |
| EP-2013166-B1 | N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE | AKCIJU SABIEDRIBA OLAINFARM (LV) | 2010-03-10 | — | — | EP | claimed |
| US-20100022784-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | Joint Stock Company "Olainfarm" (LV) | 2010-01-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022784-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | PRMT6, CPS1, JMJD6 | ALDH1A1 3160/4885POLB 1370/4885L3MBTL1 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.