Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 7/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335829 | 0.84 | ATM (0.48) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL664847 | 0.83 | HTR2C (0.53) | KDM4EALDH1A1GLAHPGDATM | |
| SCHEMBL21285157 | 0.81 | ESR1 (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL12352 | 0.78 | ATM (0.56) | KDM4EATMHTR2APDE4APDE4B | |
| SCHEMBL29555842 | 0.78 | ATM (0.56) | KDM4EATMHTR2APDE4APDE4B | |
| SCHEMBL3263472 | 0.78 | HTR2C (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29638857 | 0.76 | SRC (0.48) | KDM4EALDH1A1HPGDATMHTR2C | |
| SCHEMBL435044 | 0.76 | SRC (0.48) | KDM4EALDH1A1HPGDATMHTR2C | |
| SCHEMBL6498321 | 0.75 | HTR2C (0.51) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL12980993 | 0.75 | ATM (0.52) | ATMHTR2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808721-B2 | Bed bug attractants and methods for trapping bed bugs | SPRINGSTAR INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-20120285076-A1 | BED BUG ATTRACTANTS AND METHODS FOR TRAPPING BED BUGS | SPRINGSTAR INC. (US) | 2012-11-15 | — | — | US | claimed |
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| US-20050227994-A1 | Decomposition inhibitor for extracellular matrix of cartilage | SHIONOGI & CO., LTD. | 2005-10-13 | — | — | US | claimed |
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | L'OREAL (FR) | 2004-10-21 | — | — | US | claimed |
| EP-0446132-B1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5279620-A | Containg paraphenylenediamine, para-aminophenol and paraheterocyclic precursors | L'OREAL (FR) | 1994-01-18 | — | — | US | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | claimed |
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20130012754-A1 | MICROWAVE INDUCED PHOTODYNAMIC THERAPY | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2013-01-10 | — | — | US | disclosed |
| US-20110263435-A1 | GENETIC MARKERS FOR BOAR TAINT | UNIVERSITY OF GUELPH (CA) | 2011-10-27 | — | — | US | disclosed |
| CN-102143946-A | Calcium channel modulators and uses thereof | LECTUS THERAPEUTICS LTD | 2011-08-03 | — | — | CN | disclosed |
| US-5279620-A | Containg paraphenylenediamine, para-aminophenol and paraheterocyclic precursors | L'OREAL (FR) | 1994-01-18 | — | — | US | disclosed |
| US-5207798-A | Hair dyes | L'OREAL (FR) | 1993-05-04 | — | — | US | disclosed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | CDC73, KRT18, PAH | KDM4E 1179/4885ALDH1A1 1045/4885GLA 3450/4885 |
| US-20050227994-A1 | Decomposition inhibitor for extracellular matrix of cartilage | MMP1, COL2A1, MMP13 | KDM4E 721/4885ALDH1A1 342/4885GLA 57/4885 |
| US-20130012754-A1 | MICROWAVE INDUCED PHOTODYNAMIC THERAPY | PPIF, MSH6, PPOX | KDM4E 4292/4885ALDH1A1 1884/4885GLA 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.