Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373732 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2CYP19A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11367471 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16128963 | 0.81 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL3738321 | 0.80 | HDAC3 (0.39) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3715907 | 0.78 | ALDH1A1 (0.37) | CYP19A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16128966 | 0.77 | HDAC3 (0.43) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11371068 | 0.76 | KMT2A (0.45) | SMN1; SMN2KMT2AMEN1HCRTR1POLB | |
| SCHEMBL10818451 | 0.74 | POLB (0.42) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16128961 | 0.73 | MAPT (0.41) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2772007 | 0.73 | HDAC3 (0.34) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-02-03 | — | — | US | claimed |
| EP-4514595-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| EP-4240578-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2024-12-18 | — | — | EP | claimed |
| US-11886045-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-01-30 | — | — | US | claimed |
| US-11834383-B2 | Energetic feedstock for additive manufacturing | LYNNTECH, INC. (US) | 2023-12-05 | — | — | US | claimed |
| WO-2023209570-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| US-20230339149-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-10-26 | — | — | US | claimed |
| EP-4240578-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-09-13 | — | — | EP | claimed |
| US-11708446-B2 | Polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-25 | — | — | US | claimed |
| EP-3976878-B1 | METHODS OF MAKING A DEFLECTION MEMBER | PROCTER & GAMBLE (US) | 2023-07-05 | — | — | EP | claimed |
| US-20220137433-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-05-05 | — | — | US | claimed |
| EP-3976878-A1 | METHODS OF MAKING A DEFLECTION MEMBER | The Procter & Gamble Company (US) | 2022-04-06 | — | — | EP | claimed |
| US-20210276931-A1 | Energetic Feedstock for Additive Manufacturing | LYNNTECH, INC. | 2021-09-09 | — | — | US | claimed |
| US-20210221937-A1 | POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-07-22 | — | — | US | claimed |
| US-11041026-B2 | Reactions enabled by thermoresponsive and photoresponsive gels | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | claimed |
| WO-2018140977-A1 | REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-08-02 | — | — | WO | claimed |
| US-20160244546-A1 | DIRECT SYNTHESIS OF PH-RESPONSIVE POLYMER PARTICLES AND APPLICATION IN CONTROL RELEASE OF HYDROPHOBIC THERAPEUTIC COMPOUNDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-08-25 | — | — | US | claimed |
| WO-2015053716-A1 | DIRECT SYNTHESIS OF PH-RESPONSIVE POLYMER PARTICLES AND APPLICATION IN CONTROL RELEASE OF HYDROPHOBIC THERAPEUTIC COMPOUNDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-04-16 | — | — | WO | claimed |
| WO-1989008830-A1 | THIOACYLATION PEPTIDE SEQUENCING WITH ALCOHOLYSIS OF THIAZOLINONES | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-21 | — | — | WO | claimed |
| US-4863870-A | Method of thioacylation peptide sequencing with alcoholysis of thiazolinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | INF2, CRYZ, CRYAA | SMN1; SMN2 4286/4885CYP19A1 788/4885HDAC3 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.