Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262218 | 0.84 | NPSR1 (0.49) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL3261819 | 0.80 | KMT2A (0.44) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL3264256 | 0.76 | GAA (0.41) | RAB9ASMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL3263163 | 0.75 | POLB (0.46) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL3262626 | 0.75 | L3MBTL1 (0.42) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL4213757 | 0.69 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL4208305 | 0.69 | NPSR1 (0.51) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL4054606 | 0.69 | LMNA (0.48) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL23558009 | 0.68 | SMN1; SMN2 (0.65) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL1803890 | 0.68 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |