SCHEMBL3369640

SCHEMBL3369640

CC[C](CC)c1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
GSK3B P49841 3/20 0.44
OGG1 O15527 1/20 0.43
HDAC3 O15379 3/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC2 Q92769 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
DUSP3 P51452 1/20 0.42
PTPN5 P54829 1/20 0.42
PTPN11 Q06124 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CYP2A6 P11509 1/20 0.42
HDAC10 Q969S8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3989195 0.76 ALDH1A1 (0.48) HTTCES2CES1GSK3BHDAC1
SCHEMBL5178198 0.75 MAOA (0.47) HTTCES2CES1GSK3BOGG1
SCHEMBL22641377 0.75 HTT (0.46) HTTCES2CES1GSK3BOGG1
SCHEMBL301100 0.75 GSK3B (0.64) HTTCES2CES1GSK3BOGG1
SCHEMBL3264307 0.74 CYP19A1 (0.58) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL4884033 0.74 HTR7 (0.47) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL23145325 0.73 HTT (0.44) HTTCES2CES1GSK3BOGG1
SCHEMBL23145395 0.73 HTT (0.44) HTTCES2CES1GSK3BOGG1
SCHEMBL23145323 0.73 HTT (0.44) HTTCES2CES1GSK3BOGG1
Propane SCHEMBL27739979 0.73 CYP2A6 (0.67) CES2CES1CA1CA2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015005680-A1 GERMANIUM-CENTERED DENDRIMER COMPOUND, AND ORGANIC OPTOELECTRIC ELEMENT COMPRISING SAME 중앙대학교 산학협력단 (KR) 2015-01-15 WO disclosed
EP-2236488-A1 Materials, methods and uses for photochemical generation of acids and/or radical species The Arizona Board of Regents on behalf of the University of Arizona (US) 2010-10-06 EP disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
US-20050173683-A1 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) 2005-08-11 US disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed