Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261663 | 0.83 | NPSR1 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL3264571 | 0.80 | RAB9A (0.42) | KMT2ASMN1; SMN2MEN1PLK1ALDH1A1 | |
| SCHEMBL3260654 | 0.78 | MAPT (0.50) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL3264376 | 0.75 | CYP1A2 (0.40) | KMT2ASMN1; SMN2MEN1LMNAATM | |
| SCHEMBL3390240 | 0.75 | PLK1 (0.39) | PLK1ALDH1A1MAPTHTTHPGD | |
| SCHEMBL3263163 | 0.74 | POLB (0.46) | KMT2ASMN1; SMN2MEN1PLK1ALDH1A1 | |
| SCHEMBL3262626 | 0.74 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2MEN1PLK1ALDH1A1 | |
| SCHEMBL23558009 | 0.70 | SMN1; SMN2 (0.65) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL16872784 | 0.70 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL27938726 | 0.70 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |