SCHEMBL3265245

SCHEMBL3265245

CCCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCCC)(CCCCCCCCCCCCCCCCCCC)NC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.60
HSP90AA1 P07900 1/20 0.55
ALDH1A1 P00352 3/20 0.55
FAAH O00519 6/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK1 P28482 1/20 0.50
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
PPARG P37231 6/20 0.45
PPARD Q03181 6/20 0.45
PPARA Q07869 6/20 0.45
HDAC11 Q96DB2 5/20 0.45
TSHR P16473 4/20 0.45
GPR84 Q9NQS5 4/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
PTPN1 P18031 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8498722 0.91 HRH3 (0.69) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL8499436 0.91 HRH3 (0.69) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL8496596 0.87 HRH3 (0.64) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL16214678 0.84 HRH3 (0.81) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL7737049 0.84 HRH3 (0.81) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL2907984 0.84 HRH3 (0.81) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL3760754 0.84 HRH3 (0.81) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL1221877 0.84 HRH3 (0.81) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL8495755 0.84 HRH3 (0.49) HRH3HSP90AA1ALDH1A1FAAHMEN1
SCHEMBL19783828 0.82 ALDH1A1 (0.75) HRH3HSP90AA1ALDH1A1FAAHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8568808-B2 Intercalated layered silicate CRYOVAC, INC. (US) 2013-10-29 US disclosed
US-20100040653-A1 Intercalated layered silicate CRYOVAC, INC. 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040653-A1 Intercalated layered silicate SMC4, SMC1A, SMCHD1 HRH3 4529/4885HSP90AA1 762/4885ALDH1A1 2698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.