SCHEMBL32661872

SCHEMBL32661872

NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccncc4)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 1/20 0.64
DNMT1 P26358 1/20 0.64
DNMT3B Q9UBC3 1/20 0.64
SLC29A1 Q99808 3/20 0.63
ADORA3 P0DMS8 4/20 0.62
TP53 P04637 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
NT5E P21589 1/20 0.61
UBA6 A0AVT1 1/20 0.60
ATG7 O95352 1/20 0.60
UBA7 P41226 1/20 0.60
NAE1 Q13564 1/20 0.60
UBA3 Q8TBC4 1/20 0.60
SAE1 Q9UBE0 1/20 0.60
P2RX3 P56373 1/20 0.60
P2RX2 Q9UBL9 1/20 0.60
ADORA2A P29274 1/20 0.60
ADORA1 P30542 1/20 0.60
PRKAG1 P54619 1/20 0.59
PRKAA1 Q13131 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1796735 0.92 DNPH1 (0.75) DNPH1DNMT1DNMT3BSLC29A1ADORA3
SCHEMBL17889870 0.92 DNPH1 (0.75) DNPH1DNMT1DNMT3BSLC29A1ADORA3
SCHEMBL1794568 0.91 SLC29A1 (0.64) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL12652413 0.91 SLC29A1 (0.64) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL1796050 0.91 SLC29A1 (0.64) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL32662526 0.90 ADORA3 (0.76) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL1799750 0.87 SLC29A1 (0.60) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL1797185 0.86 ADORA3 (0.75) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL32661694 0.86 UBA6 (0.63) DNPH1SLC29A1ADORA3TP53TDP1
SCHEMBL17889823 0.86 ADORA3 (0.67) DNPH1SLC29A1ADORA3TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015592-A1 NEDDYLATION-ACTIVATING ENZYME INHIBITORS AS VIRAL SENSITIZERS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2026-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015592-A1 NEDDYLATION-ACTIVATING ENZYME INHIBITORS AS VIRAL SENSITIZERS AND USES THEREOF NAE1, NEDD8, UBA3 DNPH1 730/4885DNMT1 593/4885DNMT3B 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.