Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GALR2 | O43603 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359182 | 0.85 | LMNA (0.61) | LMNAALDH1A1SMN1; SMN2KMT2APTBP1 | |
| SCHEMBL3266479 | 0.84 | SMN1; SMN2 (0.60) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL14496904 | 0.81 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2MITFHSP90AA1 | |
| SCHEMBL11237157 | 0.81 | POLB (0.60) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL10936842 | 0.79 | MAPT (0.55) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL2929136 | 0.79 | NPSR1 (0.51) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL29784832 | 0.79 | LMNA (0.55) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL2205405 | 0.79 | LMNA (0.55) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL5951849 | 0.78 | KMT2A (0.53) | LMNAALDH1A1SMN1; SMN2POLBGALR2 | |
| SCHEMBL9721603 | 0.78 | ALDH1A1 (0.58) | LMNAALDH1A1SMN1; SMN2POLBGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472213-B1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | WYETH LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| US-7294740-B2 | Process for the synthesis of N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids | WYETH (US) | 2007-11-13 | — | — | US | disclosed |
| US-20070219394-A1 | Process for the synthesis of N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
| US-7227037-B2 | Process for the synthesis of N-nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids | WYETH (US) | 2007-06-05 | — | — | US | disclosed |
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1549297-A2 | STABILIZED PHARMACEUTICAL COMPOSITION CONTAINING BASIC EXCIPIENTS | Wyeth Holdings Corporation (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20050085662-A1 | Process for the synthesis of nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids | WYETH (US) | 2005-04-21 | — | — | US | disclosed |
| EP-1472213-A1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | Wyeth (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040122048-A1 | Stabilized pharmaceutical composition containing basic excipients | WYETH HOLDINGS CORPORATION | 2004-06-24 | — | — | US | disclosed |
| WO-2004032909-A2 | STABILIZED PHARMACEUTICAL COMPOSITION CONTAINING BASIC EXCIPIENTS | WYETH HOLDINGS CORPORATION (US) | 2004-04-22 | — | — | WO | disclosed |
| WO-2003066575-A1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | WYETH (US) | 2003-08-14 | — | — | WO | disclosed |
| EP-1263503-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6384051-B1 | ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY | 2002-05-07 | — | — | US | disclosed |
| WO-2001068186-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219394-A1 | Process for the synthesis of N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids | NAAA, ARSA, ACMSD | LMNA 2389/4885ALDH1A1 1206/4885SMN1; SMN2 1470/4885 |
| US-20050085662-A1 | Process for the synthesis of nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids | NAAA, ACMSD, ASNS | LMNA 3608/4885ALDH1A1 1292/4885SMN1; SMN2 2190/4885 |
| US-20040122048-A1 | Stabilized pharmaceutical composition containing basic excipients | F7, H1-10, F12 | LMNA 1455/4885ALDH1A1 3199/4885SMN1; SMN2 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.