Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665006 | 0.89 | KDM4E (0.42) | AKR1C2AKR1C1DHODHKDM4EMAPT | |
| SCHEMBL32664975 | 0.85 | ALDH1A1 (0.52) | DHODHKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL32664893 | 0.85 | CAMKK2 (0.43) | AKR1C2AKR1C1DHODHKDM4EMAPT | |
| SCHEMBL32664937 | 0.82 | RXRA (0.47) | DHODHKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6508314 | 0.82 | AKR1C2 (0.70) | AKR1C2AKR1C1DHODHSMN1; SMN2MCL1 | |
| SCHEMBL32665023 | 0.81 | KMO (0.45) | KDM4EMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL32665317 | 0.80 | KDR (0.43) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL32665218 | 0.80 | ALDH1A1 (0.49) | DHODHKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL26459335 | 0.78 | PRMT5 (0.44) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL32665100 | 0.76 | RAB9A (0.49) | KDM4EMAPTALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV MINNESOTA (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | NR5A1, CYP17A1, CNR1 | AKR1C2 215/4885AKR1C1 253/4885DHODH 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.