Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | CCR6 | P51684 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665143 | 0.92 | L3MBTL3 (0.37) | L3MBTL1L3MBTL3ALDH1A1TDP1GAA | |
| SCHEMBL32665103 | 0.89 | ALDH1A1 (0.33) | ALDH1A1TDP1GAALMNAHSP90AA1 | |
| SCHEMBL32665174 | 0.86 | NOTUM (0.40) | NOTUML3MBTL1L3MBTL3ALDH1A1 | |
| SCHEMBL32665450 | 0.86 | NOTUM (0.40) | NOTUML3MBTL1L3MBTL3ALDH1A1 | |
| SCHEMBL32665268 | 0.79 | CYP2C9 (0.33) | HRH3ALDH1A1TDP1LMNAHSP90AA1 | |
| SCHEMBL32665285 | 0.79 | ALDH1A1 (0.36) | NOTUML3MBTL1L3MBTL3ALDH1A1MAPT | |
| SCHEMBL32665425 | 0.76 | TDP1 (0.44) | HRH3NOTUML3MBTL1L3MBTL3ALDH1A1 | |
| SCHEMBL32665396 | 0.76 | HRH1 (0.35) | HRH3L3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL32665632 | 0.74 | CHRM4 (0.36) | DRD2L3MBTL1ALDH1A1TDP1KDM4E | |
| SCHEMBL17318128 | 0.64 | CA2 (0.52) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | DRD2 4539/4885DRD4 4678/4885CCNC 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.