Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 8/20 | 0.36 |
| ▸ | HTR7 | P34969 | 7/20 | 0.36 |
| ▸ | HTR6 | P50406 | 7/20 | 0.36 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665396 | 0.88 | HRH1 (0.35) | CHRM4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL32665021 | 0.87 | HTR1A (0.38) | CHRM4HTR7HTR6DRD2HTR1A | |
| SCHEMBL32665143 | 0.81 | L3MBTL3 (0.37) | ALDH1A1GAATDP1L3MBTL1 | |
| SCHEMBL32665151 | 0.78 | ME3 (0.43) | CHRM4HTR7ACHEKDM4EGAA | |
| SCHEMBL32665195 | 0.75 | HRH1 (0.37) | CHRM4HTR1AKDM4EALDH1A1GAA | |
| SCHEMBL32665356 | 0.74 | DRD2 (0.34) | DRD2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL32665103 | 0.70 | ALDH1A1 (0.33) | ALDH1A1GAATDP1 | |
| SCHEMBL32665419 | 0.69 | DRD2 (0.46) | CHRM4HTR7DRD2ACHEMAPT | |
| SCHEMBL32665268 | 0.69 | CYP2C9 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL32665550 | 0.68 | MGLL (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CHRM4 4725/4885HTR7 4312/4885HTR6 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.