Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.98 |
| ▸ | HTR2A | P28223 | 8/20 | 0.57 |
| ▸ | MPO | P05164 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.47 |
| ▸ | HTR1B | P28222 | 4/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633073 | 0.99 | HTR1A (1.00) | HTR1AHTR2AMPOHTR2CHTR2B | |
| SCHEMBL20970863 | 0.99 | HTR1A (1.00) | HTR1AHTR2AMPOHTR2CHTR2B | |
| SCHEMBL32669346 | 0.86 | HTR1A (0.78) | HTR1AHTR2AMPOHTR2CHTR2B | |
| SCHEMBL8548458 | 0.84 | HTR1A (0.74) | HTR1AHTR2AMPOHTR2CHTR2B | |
| SCHEMBL24723416 | 0.81 | HTR1A (0.70) | HTR1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL32669272 | 0.80 | HTR2A (0.67) | HTR1AHTR2AMPOHTR2CHTR2B | |
| SCHEMBL32669438 | 0.79 | HTR1A (0.72) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL26508356 | 0.79 | HTR1A (0.66) | HTR1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL32669276 | 0.78 | HTR1A (0.71) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL30916159 | 0.76 | HTR1A (1.00) | HTR1AHTR2AMPOHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034119-A1 | 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034119-A1 | 5-METHOXY-N,N-DIMETHYLTRYPTAMINE ANALOGS, THEIR SYNTHESIS, AND METHODS FOR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC, AND SUBSTANCE USE DISORDERS | HTR4, OPRM1, HTR7 | HTR1A 4/4885HTR2A 12/4885MPO 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.