Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GYS1 | P13807 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495080 | 0.79 | L3MBTL1 (0.55) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL3267568 | 0.78 | AKT2 (0.56) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL6854551 | 0.74 | L3MBTL1 (0.65) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL13715627 | 0.65 | ABCC8 (0.56) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL3261526 | 0.65 | LRRK2 (0.51) | KMT2AAKT2CHEK1ALDH1A1POLB | |
| SCHEMBL7779584 | 0.64 | PTGS2 (0.58) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL3263313 | 0.64 | ALK (0.47) | AKT2CHEK1ALDH1A1JAK2LMNA | |
| SCHEMBL3390214 | 0.64 | IKBKB (0.55) | MAPTCNR1CNR2GPR55KMT2A | |
| SCHEMBL3261336 | 0.63 | HSP90AA1 (0.48) | L3MBTL1MAPTCNR1CNR2GPR55 | |
| SCHEMBL8629976 | 0.62 | L3MBTL1 (0.51) | L3MBTL1MAPTCNR1CNR2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |