Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.43 |
| ▸ | CDK2 | P24941 | 7/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679532 | 0.84 | CCNE1 (0.49) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL15344975 | 0.71 | SORD (0.48) | — | |
| SCHEMBL15749181 | 0.70 | EGFR (0.69) | CDK2 | |
| SCHEMBL17661179 | 0.68 | TBK1 (0.51) | ROCK2 | |
| SCHEMBL15341857 | 0.68 | SORD (0.41) | ACHE | |
| SCHEMBL26106026 | 0.65 | ACHE (0.47) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL15698538 | 0.65 | CCNE1 (0.61) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL25630336 | 0.65 | MAPK8 (0.52) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL30682482 | 0.65 | DPP4 (0.36) | — | |
| SCHEMBL19957592 | 0.63 | ACHE (0.47) | ROCK2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120647626-B | 4-Aminopyrimidine compound targeting EGFR and AXL targets as well as preparation method and application thereof | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | 2026-02-27 | — | — | CN | disclosed |