Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 10/20 | 0.49 |
| ▸ | CDK2 | P24941 | 10/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679538 | 0.84 | CCNE1 (0.43) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL28296626 | 0.72 | ACHE (0.50) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL12783965 | 0.72 | PAK4 (0.74) | — | |
| SCHEMBL4117914 | 0.72 | L3MBTL3 (0.73) | — | |
| SCHEMBL25630336 | 0.71 | MAPK8 (0.52) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL15698538 | 0.71 | CCNE1 (0.61) | CCNE1CDK2ROCK2ROCK1ACHE | |
| SCHEMBL27810118 | 0.71 | KDM4E (0.53) | — | |
| SCHEMBL4938363 | 0.70 | L3MBTL3 (0.71) | — | |
| SCHEMBL15827573 | 0.70 | ACHE (0.44) | CCNE1CDK2ACHEEGFR | |
| SCHEMBL25630335 | 0.69 | ROCK2 (0.68) | ROCK2ROCK1ACHEHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120647626-B | 4-Aminopyrimidine compound targeting EGFR and AXL targets as well as preparation method and application thereof | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | 2026-02-27 | — | — | CN | disclosed |