Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506944 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL3268166 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AIDO1MAOB | |
| SCHEMBL5628701 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL2658182 | 0.84 | CCR5 (0.48) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL5628276 | 0.83 | MEN1 (0.53) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL3269606 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL3271842 | 0.80 | MAOB (0.52) | ALDH1A1MEN1HPGDKMT2ACYP1A2 | |
| SCHEMBL2650190 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1HPGDKMT2ACYP1A2MAOB | |
| SCHEMBL2289832 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL5627381 | 0.77 | PTGER1 (0.55) | ALDH1A1MEN1POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | ALDH1A1 381/4885MEN1 1138/4885POLB 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.