SCHEMBL4506944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3267969	0.87	ALDH1A1 (0.47)	ALDH1A1PTGER1CYP1A2POLBMEN1
	SCHEMBL3267315	0.84	HPGD (0.49)	ALDH1A1SMN1; SMN2LMNAHTTNPSR1
	SCHEMBL3269606	0.79	SMN1; SMN2 (0.47)	ALDH1A1SMN1; SMN2LMNAHTTL3MBTL1
	SCHEMBL3268166	0.79	ALDH1A1 (0.49)	ALDH1A1SMN1; SMN2LMNAHTTNPSR1
	SCHEMBL3271842	0.78	MAOB (0.52)	ALDH1A1SMN1; SMN2LMNACYP1A2CYP3A4
	SCHEMBL2650190	0.78	SMN1; SMN2 (0.43)	ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
	SCHEMBL3267168	0.78	MRGPRX4 (0.43)	SMN1; SMN2HTTHSD17B10L3MBTL1KMT2A
	SCHEMBL8371564	0.73	POLB (0.54)	ALDH1A1SMN1; SMN2HTTPTGER1CYP1A2
	SCHEMBL2664414	0.73	KMT2A (0.49)	ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
	SCHEMBL3272664	0.73	ENPP2 (0.52)	ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.