Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565254 | 0.87 | IKBKB (0.67) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL13631960 | 0.81 | ITGA1 (1.00) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL4815316 | 0.80 | ITGA1 (0.67) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL14018772 | 0.80 | MAPT (0.63) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL21545964 | 0.79 | NR4A2 (0.55) | ITGA1MAPK1CMA1LMNAHPGD | |
| SCHEMBL8274502 | 0.79 | HDAC1 (0.74) | ITGA1MAPK1HDAC1HDAC8 | |
| SCHEMBL4882914 | 0.77 | PGR (0.61) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL4880041 | 0.77 | SGK1 (0.55) | ITGA1HDAC1HDAC8LMNAMEN1 | |
| SCHEMBL94831 | 0.77 | MAPT (0.63) | ITGA1MAPK1HDAC1HDAC8LMNA | |
| SCHEMBL28121241 | 0.77 | MAPT (0.63) | ITGA1MAPK1HDAC1HDAC8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | ITGA1 3624/4885MAPK1 167/4885CMA1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.