Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.63 |
| ▸ | ITGA1 | P56199 | 4/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | SGK1 | O00141 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118839 | 0.87 | ALDH1A1 (0.67) | MAPTMEN1KMT2ALMNAPRMT1 | |
| SCHEMBL4882914 | 0.84 | PGR (0.61) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL94831 | 0.84 | MAPT (0.63) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL14018772 | 0.84 | MAPT (0.63) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL7577795 | 0.83 | ITGA1 (0.74) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL28513733 | 0.83 | MEN1 (0.66) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL3268657 | 0.82 | MAPT (0.61) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL3267463 | 0.81 | HDAC1 (0.66) | MAPTMEN1KMT2ALMNAALOX12 | |
| Propane SCHEMBL7212983 | 0.81 | TP53 (0.54) | MAPTMEN1KMT2ALMNAALOX12 | |
| SCHEMBL3267231 | 0.80 | ITGA1 (0.61) | MAPTMEN1KMT2ALMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431998-A | N-[4-(isopimaric acid acylamino)phenyl]arylsulfonamide compounds and preparation method and anticancer activity application thereof | 中国林业科学研究院林产化学工业研究所 | 2017-02-22 | — | — | CN | disclosed |