Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.67 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268660 | 0.87 | ITGA1 (0.68) | ITGA1HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL12971607 | 0.85 | LMNA (0.79) | IKBKBHPGDLMNARECQLALDH1A1 | |
| SCHEMBL28280869 | 0.79 | NHERF1 (0.71) | IKBKBCA1CA2HPGDLMNA | |
| SCHEMBL7570508 | 0.79 | TSHR (0.64) | ITGA1HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL4815316 | 0.79 | ITGA1 (0.67) | ITGA1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2825347 | 0.77 | LMNA (0.59) | IKBKBHPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL8274502 | 0.77 | HDAC1 (0.74) | ITGA1MAPK1HDAC1HDAC8 | |
| SCHEMBL16049705 | 0.77 | CA1 (0.59) | IKBKBCA1CA2HPGDLMNA | |
| SCHEMBL13631960 | 0.77 | ITGA1 (1.00) | ITGA1HPGDLMNAMEN1KMT2A | |
| SCHEMBL2910759 | 0.77 | CMA1 (0.82) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | IKBKB 4299/4885ITGA1 3624/4885CA1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.